Absorption: Modafinil is quickly absorbed right after oral administration. It truly is insoluble in an aqueous Resolution and so can not be administered intravenously. Most plasma focus is reached two to four hrs after administration. 

Serum concentrations of modafinil may very well be lessened into a clinically considerable extent in the presence of drugs that induce CYP3A4. These incorporate rifampin, phenytoin, St John Wort, and efavirenz.

Use with caution in serious hepatic impairment, elderly, and individuals with a heritage of despair or psychosis (modafinil might exacerbate psychiatric symptoms) or mania

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For those who have slumber apnea and utilize a constant optimistic airway stress (CPAP) equipment in the evening, keep on making use of this machine with modafinil.

Slumber apnea is often a ailment exactly where sleep is consistently interrupted in the evening due to pauses in respiratory or shallow respiration normally on account of obstruction from the higher airway.

Making use of this drugs with any of the next medicines is usually not suggested, but might be needed sometimes. If equally medicines are prescribed with each other, your health practitioner may possibly change the dose or how often you utilize just one or both equally of the medicines.

It's a ailment that triggers an individual to intermittently halt breathing through sleep. Warning signs of rest apnea involve snoring, nighttime gasping, intermittent pauses all through rest, and daytime sleepiness.

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The existence of other clinical issues might influence the use of this medicine. Make sure you explain to your medical doctor When you've got every other clinical challenges, In particular:

Your healthcare company may keep an eye on you intently if you have had a modern coronary heart assault or have upper body pain linked to little or no action. Halt getting modafinil and have crisis assistance straight away.

Pregnancy: It is assessed as pregnancy class C medicine through the FDA. There isn't any proof to counsel or exclude harm towards the human fetus connected with modafinil.

Adhere to the directions and rules provided by your healthcare service provider when taking the “clever drug” or every other medication.